The CZ110 is a semi-auto pistol, which uses 9x19 mm parabellum, 9x21mm IMI and .40 s&w rounds.
The CZ 110 is a recoil operated, locked breech semi-auto pistol, it features a short recoil barrel that locks with the slides with a single massive lug which engages the ejection port cut-out when locked.
The frame of CZ 110 is made from impact resistant polymer, with slides made up of steel. It is a striker fired pistol, the striker can be fully cocked by slide mechanism and if immediate fire is not required the striker can be brought to rest by docking lever.
It includes safeties like automated firing pin block and loaded chamber indicator. It also features an accessory rail on which tactical lights and lazer pointer can be installed.
It has a double action trigger but it can also use single action firing if the striker is fully cocked.